Lars Arendt-Nielsen Selected Research

Neurogenic Inflammation

1/2022	Effects of Salicornia-Based Skin Cream Application on Healthy Humans' Experimental Model of Pain and Itching.
1/2021	Effect of Topical Analgesia on Desensitization Following 8% Topical Capsaicin Application.
9/2017	Dose-response study of topical allyl isothiocyanate (mustard oil) as a human surrogate model of pain, hyperalgesia, and neurogenic inflammation.
1/2017	Antipruritic Effect of Cold-induced and Transient Receptor Potential-agonist-induced Counter-irritation on Histaminergic Itch in Humans.
1/2016	High-Concentration L-Menthol Exhibits Counter-Irritancy to Neurogenic Inflammation, Thermal and Mechanical Hyperalgesia Caused by Trans-cinnamaldehyde.
2/2014	Time course analysis of the effects of botulinum neurotoxin type A on pain and vasomotor responses evoked by glutamate injection into human temporalis muscles.
2/2011	Capsaicin-induced neurogenic inflammation in the skin in patients with symptoms induced by odorous chemicals.
8/2010	Cutaneous nociception and neurogenic inflammation evoked by PACAP38 and VIP.
1/2009	Subcutaneous Botulinum toxin type A reduces capsaicin-induced trigeminal pain and vasomotor reactions in human skin.
5/2006	Transient cold pain has no effect on cutaneous vasodilatation induced by capsaicin: a randomized-control-crossover study in healthy subjects.

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Lars Arendt-Nielsen Research Topics

Disease

289	Pain (Aches) 12/2022 - 01/2000
80	Hyperalgesia 01/2022 - 04/2000
36	Myalgia 12/2019 - 01/2000
35	Chronic Pain 01/2022 - 07/2005
24	Knee Osteoarthritis 01/2022 - 01/2012
20	Postoperative Pain 03/2022 - 05/2003
20	Osteoarthritis 01/2022 - 01/2011
17	Referred Pain 01/2018 - 04/2000
16	Hypersensitivity (Allergy) 09/2017 - 09/2005
15	Inflammation (Inflammations) 01/2022 - 09/2002
14	Neuralgia (Stump Neuralgia) 01/2022 - 03/2002
10	Neurogenic Inflammation 01/2022 - 05/2006
10	Visceral Pain 03/2019 - 07/2006
9	Migraine Disorders (Migraine) 01/2022 - 09/2005
8	Low Back Pain (Lumbago) 01/2019 - 05/2007
5	COVID-19 12/2022 - 01/2021
5	Acute Pain 08/2021 - 10/2003
5	Headache (Headaches) 02/2020 - 06/2007
5	Pelvic Pain 01/2020 - 05/2014
5	Nociceptive Pain 03/2019 - 10/2003
4	Peripheral Nervous System Diseases (PNS Diseases) 01/2022 - 01/2017
4	Hip Osteoarthritis (Coxarthrosis) 11/2021 - 05/2013
4	Erythema 09/2021 - 02/2011
4	Knee Injuries (Knee Injury) 02/2020 - 01/2012
4	Musculoskeletal Pain 09/2017 - 11/2007
4	Phantom Limb (Phantom Limbs) 02/2013 - 04/2008
4	Temporomandibular Joint Disorders (Temporomandibular Joint Disorder) 01/2010 - 01/2004
3	Fatigue 01/2022 - 04/2002
3	Fibromyalgia (Fibrositis) 05/2021 - 04/2000
3	Chronic Pancreatitis 03/2019 - 01/2007
3	Tension-Type Headache (Tension Headache) 01/2019 - 02/2017
3	Arthralgia (Joint Pain) 09/2017 - 04/2014
3	Neck Pain (Cervicalgia) 01/2017 - 07/2011

Drug/Important Bio-Agent (IBA)

61	Analgesics (Analgesic Drugs)IBA 01/2022 - 03/2002
52	Capsaicin (Zostrix)FDA Link 01/2022 - 01/2002
29	Biomarkers (Surrogate Marker)IBA 12/2022 - 01/2007
27	Glutamic Acid (Glutamate)FDA Link 12/2019 - 01/2003
24	Pain-FreeIBA 01/2022 - 09/2000
20	Opioid Analgesics (Opioids)IBA 10/2021 - 09/2002
20	Pharmaceutical PreparationsIBA 01/2021 - 04/2000
12	Nerve Growth Factor (NGF)IBA 01/2021 - 07/2003
12	Ketamine FDA LinkGeneric 04/2012 - 04/2000
11	AcidsIBA 10/2017 - 09/2002
11	Oxycodone (Oxycontin)FDA LinkGeneric 10/2017 - 07/2006
10	N-Methylaspartate (NMDA)IBA 04/2012 - 04/2000
9	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 01/2018 - 03/2002
8	Histamine (Histamine Dihydrochloride)FDA Link 01/2022 - 01/2017
8	Morphine (MS Contin)FDA LinkGeneric 08/2010 - 03/2003
7	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 05/2022 - 11/2016
7	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 04/2012 - 09/2002
7	Bee Venoms (Bee Venom)IBA 03/2008 - 09/2002
6	antineoplaston A10 (A 10)IBA 01/2022 - 01/2003
6	CytokinesIBA 01/2020 - 05/2014
6	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2006
5	Indicators and Reagents (Reagents)IBA 01/2019 - 05/2004
5	Menthol FDA Link 01/2017 - 02/2013
5	Type A Botulinum Toxins (Botox)FDA Link 02/2014 - 06/2006
4	Nicotine FDA Link 11/2022 - 01/2016
4	Local AnestheticsIBA 01/2021 - 01/2004
4	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 02/2020 - 01/2011
4	Acetaminophen (Paracetamol)FDA LinkGeneric 11/2019 - 09/2007
4	cinnamaldehyde (cinnamic aldehyde)FDA Link 01/2017 - 01/2016
3	Lidocaine (Xylocaine)FDA LinkGeneric 01/2021 - 09/2005
3	C-Reactive ProteinIBA 01/2021 - 09/2014
3	MicroRNAs (MicroRNA)IBA 01/2020 - 10/2016
3	Biological ProductsIBA 01/2020 - 01/2016
3	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2019 - 07/2016
3	Gabapentin (Neurontin)FDA LinkGeneric 01/2018 - 09/2007
3	Imipramine (Janimine)FDA LinkGeneric 01/2018 - 09/2009
3	salicylhydroxamic acid (SHAM)IBA 12/2017 - 02/2011
3	SolutionsIBA 10/2017 - 03/2008
3	Opioid Receptors (Opioid Receptor)IBA 04/2013 - 08/2009
3	kappa Opioid Receptors (kappa Opioid Receptor)IBA 04/2013 - 01/2008
3	Fentanyl (Sublimaze)FDA LinkGeneric 09/2012 - 05/2003
3	6-Cyano-7-nitroquinoxaline-2,3-dione (6 Cyano 7 nitroquinoxaline 2,3 dione)IBA 09/2005 - 09/2002
3	Dizocilpine Maleate (Dizocilpine)IBA 09/2005 - 09/2002
2	CannabinoidsIBA 01/2022 - 01/2021
2	Duloxetine Hydrochloride (Cymbalta)FDA Link 01/2022 - 12/2021
2	Serotonin (5 Hydroxytryptamine)IBA 12/2021 - 01/2005
2	Antisense RNA (Anti-Sense RNA)IBA 10/2021 - 01/2020

Therapy/Procedure

25	Injections 12/2019 - 02/2003
21	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2022 - 01/2012
17	Therapeutics 01/2022 - 03/2002
17	Analgesia 01/2022 - 03/2003
14	Pain Management 01/2022 - 05/2007
14	Lasers (Laser) 01/2020 - 09/2000
14	Intramuscular Injections 12/2019 - 01/2000
8	Intradermal Injections 01/2016 - 09/2005
6	Activities of Daily Living (ADL) 02/2020 - 01/2012
5	Electrodes (Electrode) 01/2019 - 04/2002
4	Tourniquets 11/2019 - 01/2002
4	Aftercare (After-Treatment) 11/2019 - 08/2005
4	Diffuse Noxious Inhibitory Control 03/2013 - 01/2005
3	Drug Therapy (Chemotherapy) 01/2022 - 01/2007
3	Arthroplasty 11/2021 - 05/2013
3	Hysterectomy 10/2020 - 07/2015
3	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2020 - 05/2013
3	Transcutaneous Electric Nerve Stimulation (TENS) 07/2005 - 03/2003
2	Orthognathic Surgery 03/2022 - 01/2014
2	Replacement Arthroplasty 11/2021 - 02/2020